DNA interrogation by the CRISPR RNA-guided endonuclease Cas9 презентация

Ноябрь 15, 2021

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Биология
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9

Содержание

2. Martin Jinek, Jennifer A. Doudna Berkeley, California
3. CRISPR/Cas9 bacterial immune system
4. 1. Single-molecule visualization of Cas9
6. 1. Single-molecule visualization of Cas9
7. 2. Cas9-RNA finds targets by 3D diffusion
8. 3. A PAM is required for DNA interrogation
9. 4. Mechanism of RNA-DNA heteroduplex formation
10. 5. The PAM triggers Cas9 nuclease activity
12. Скачать презентацию

Слайд 2

Martin Jinek, Jennifer A. Doudna
Berkeley, California

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CRISPR/Cas9 bacterial immune system

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1. Single-molecule visualization of Cas9

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1. Single-molecule visualization of Cas9

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2. Cas9-RNA finds targets by 3D diffusion

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3. A PAM is required for DNA interrogation

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4. Mechanism of RNA-DNA heteroduplex formation

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5. The PAM triggers Cas9 nuclease activity