Содержание
- 3. Antianginal Agents 1.Organic Nitrates 2. β-Blockers 3. Calcium Channel Blockers 4. Angiotensin-Converting Enzyme Inhibitors
- 4. I. Nitrates: Nitroglycerin – Tab. 0.5 mg, Caps. with 1% oil solution, amp. 1%-2 ml, vial
- 6. Nitroglycerin - tab. 0.0005 g (0.5 mg), amp. 1%-2 ml, vial 1% spirituous sol. - 5
- 8. Clinucal uses of Nitroglycerine: Prophylaxis and Control of Angina Attack IV Infusion in Myocardial Infarction Pulmonary
- 10. Overdose With Nitroglycerine: Vasodilation and Methemoglobinemia - ⮚ Hypotension, Throbbing Headache, Palpitations, ⮚ Visual disturbances, Flushing
- 11. Treatment of overdose with nitroglycerine: Gastric Lavage; Activated Charcoal Oxygen therapy (Hyperbaric Oxygenation) Antidotes: Ascorbic acid
- 12. β-Adrenoblockers: Propranolol (Anaprilin) (β1, β2) – tab. 10 and 40 mg Timolol (β1, β2) – tab.
- 13. Ca2+ Channel Blockers I. Diphenylalkylamines: Verapamil II. Dihydropyridines: 1st Generation: Nifedipine (Adalat, Procardia) 2nd Generation: Amlodipine,
- 17. Verapamil appears to have antianginal, antihypertensive and antiarrhythmic action. It manages unstable and chronic stable angina
- 19. Nifedipine – functions mainly as an arteriolar vasodilator. It dilates systemic arteries, resulting in: ?Total Peripheral
- 20. Amlodipine is a Dihydropyridine compound – the 2nd Generation long-acting Ca2+ antagonist. It blocks the inward
- 21. The Angiotensin-Converting Enzyme (ACE) Inhibitors: Captopril, Lisinopril, Enalapril block the ACE that cleaves Angiotensin I to
- 22. Other Antianginal Drugs Antiplatelet agents: Aspirin - 0.075 – 0.325 g daily blocks formation of PG
- 24. GPIIb / IIIa antagonists - a new class of platelet–inhibiting drugs that block platelet receptors for
- 25. Coronary steal phenomenon occurs when two branches from the main coronary vessel have different degrees of
- 26. Drugs for the Treatment of Acute Myocardial Infarction The major principles treatment of AMI: Pain syndrome
- 27. Neuroleptanalgesia with Fentanyl 0.005% 2-4 ml Droperidol 0.25%-1-4 ml - is a base of all schemes
- 28. Thrombolytic Therapy: Alteplase or Streptokinase to dissolve the thrombus pharmacologically Heparin is given to prevent a
- 29. Agents Regulating Cerebral Circulation I. Agents affecting the platelet aggregation and coagulation 1. Antiaggregants (Antitplatelet Drugs):
- 30. 2. Derivatives of Vinca alkaloids - derived from the Lesser Periwinkle plant (Vinca minor): Vinpocetin (Cavinton)
- 31. Pentoxiphylline - Tab. 0.1 g, amp. 2% solution 5 ml - a Methylxanthine derivative. Mechanism of
- 32. Instenon is a combined drug for the treatment of Ischemic Cerebrovascular Diseases. It contains: Methylxanthine Ethophylline,
- 33. Vinpocetin (Cavinton) tab. 5 mg, amp. 0.5%-2 ml is an alkaloid derivative from Periwinkle (Vinca minor).
- 34. Nicergolin (Sermion) – tab. 5 mg, 10 mg; vial 4 mg IM combines the structures of
- 35. Nimodipine (Nimotop)- a Ca2+ channel blocker with mainly influence on cerebral circulation. It inhibits Ca2+ ion
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